A worried husband brought his wife to the ER. She complained of fatigue, malaise, and a severe headache. She was awake and alert with no active vomiting. She thought she had a cold and had taken over-the-counter cough medication for a week and stated that she seemed to have improved after taking the medication. She also took aspirin to relieve her headache symptoms. She also acknowledged that she experienced persistent vomiting for the past two days and took Pepto-Bismol for her upset stomach.
She denied any family history of hypertension and genetic bleeding disorders. She had no history of diarrhea, asthma, allergies, or peptic ulcer. She had a total abdominal hysterectomy four years prior and she is not currently on estrogen therapy. She stated that she noticed that her urine was bloody. She admits that she bleeds from her gums when brushing her teeth; however, her dentist told her that bleeding gums could be a sign of gingivitis. She was scheduled to see her dentist in two weeks.
Upon examination it was found that she had little pin prick bruising marks on her thighs and arms. Standard blood tests indicated low haemoglobin, low hematocrit, high reticulocytes and extremely low platelets.
What blood tests would you perform?
If her platelet counts were <20,000 /ul, is this normal?
What are the roles of platelets in hemostasis? What are the steps in hemostasis?
How are antibodies involved in the above?
How does the immune system typically avoid the above issue?
omowunmisolarin
posted on
Wed, 25 Jan 2017