Can Higher Dose Of Estrogen Shrinks Fibroid?

Hi,I have a question about my wife.My wife is 50 and has a 9cm + fibroid and i don,t want her to have surgery,She is taking fibron to shrink her large fibroid and after 6 weeks it isn,t working.So can she take a higher dose of estogen to shrink this fibroid and then a lower dose untill about 8 months to mentopause.Please i need some sound good advice.Please Respond!!!!!!Thank You.My email YYYY@YYYY