Hi, I Suffer From Severe GAD. Going Back Years Ago,

Hi,
I suffer from severe GAD. Going back years ago, I was on Paxil for 12 years and it worked great, except I gained a lot of weight. So I went off of it five years ago. Within the past five years I have been on Zoloft (1.5 years), Lexapro (l0 mgs) 1.5 years both worked great and then they lost their efficacy.

Last year, I had a bad knee injury and could not get my dr, as he was away. I went to a nurse prac. who prescribed me Effexor XR 112 mgs (yes 75 mg tablet and 37.5 table). She said most people went into remission from it forever. Well, I was fine for 6 months and then had to have knee surgery. I got my anxiety back again. Seriously, I never missed a dose of effexor xr. Well I went back to my regular doctor (not nurse) who upped the dose of effexor xr to 225 mgs. After two weeks I had to go off of it because my blood pressure skyrocketed. He tapered me off of Effexor to Prozac gradually, which was good. Now I have been on Prozac 20 mgs for 3 weeks and still feel horrible. I am so upset. I have to work, have a mortgage, etc. Do you think because I was on Effexor, being such a strong drug, that Prozac, won't work. Please any information you could give me I would soooo appreciate. Thank you.