Hi My Mom Has Emphysema COPD SHE TAKES ADVAIR TWICE

Hi my mom has emphysema COPD SHE TAKES ADVAIR TWICE DAILY AND HER ALBUTERAL INHALER THATS IT.FOR THE ILLNESS. LATELY SHE HAS BEEN HAVING PROBLEMS WITH HER BREATHING WHILE WALKING SHORT DISTANCES. WHAT DIES THIS MEAN, DOES SHE NEED SOMETHING MORE. SHE ALSO HAS A SMALL TUMOR ON ONE OR HER LOBES. COULD THAT GIVE HER BREATHING ISSUES. We didn't do anything with treating the tumor because of her age and because she is 79lbs small?