Hi My Wife Is 27 Years And She Has One

Hi my wife is 27 years and she has one miscarriage and second time we opt for pregnancy termination due to maningocole was detected in my baby. few weeks earlier my wife is gone though TB PCR test and detected with TB. She is on AKT4 from last few days.
1. Please suggest any more sensitive test to confirm the infection.
2. what are the chances to conceive again naturally.
3. how to prevent the side effects of AKT4 drugs.