Hi Sir. My Mother Us Physicist Patient From 1981. Upto

Hi sir.
My Mother us physicist patient from 1981.
Upto 2000 she was taking medicine
Licab 300.
My grandma died at 2013.and his son 2014 ie my mom's brother at both these incidents she had affected lot
From 2013
She is taking
Zosert 100mg
Lonaxep 0.25 mg
Olneaz 50 mg
From past 3 months she had affected more but these medicine s are not working as previously
Awaiting for ur response