I Have 2 Questions Regarding Glaucoma And Medications. How Quickly

I have 2 questions regarding glaucoma and medications. How quickly and how likely is it that Ziobtan will turn light green eyes brown? And -I have been on every eye drop as well as multiple drops and Diamox (now on timoptic, cosopt and ziobtan- only minimally helpful. Even when it helps to lower pressure slightly, this effect does not last more than 4-6 weeks. I have already had ALT and ISents-neither helped. Are there other reasons bedsides glaucoma which can cause unstable and inconsistent eye pressure since even Glaucoma experts cannot decide if I even have this disorder