I Have Autoimmune Disease And 2 Weeks Ago Had A

I have autoimmune disease and 2 weeks ago had a knee replacement. Dr. put me on hydrocodone for
pain along with phenergan to keep nausua away. I was terribly sick and could not take pain medication.
Is my immune system stopping the pain medication from working and making me terribly ill. I got off
all pain meds and taking extra strength tylenol.