I have kidney disease, FSGS, which was in remission, until we started to pull back on the medication, then it came back with a charge, protiens shot up and I hve had water weight gain of 20 lbs in two weeks. RX's prednisone and furosemide which brought the weight down but that didn't last and it shot back up again. I have a really enlarged penis and testicle sack baseball size, it's just weird to be so enlarged down there.