I Take Toprol For Hight Blood Pressure... 2 Pills A

I take Toprol for hight blood pressure... 2 pills a day @25 mg per tab... does this med interact with vitamins such as B 12 1000 mcg - and Fish Oil 1200 mg which has added vitamin D3 2000IU ... I also take Thyroid meds
Levothyroxin 100MCG 1 pill per day... and Colesterol meds Simvastin 40 mg I pill per day...