I'm Overweight, 45 Year Old Female. I Have Hypothyroidism Which

I'm overweight, 45 year old female. I have hypothyroidism which is managed through medication. I've gained 30 pounds in 6 months. I have been on a reduced calorie diet plus 3 different weight loss medications prescribed by Dr. I haven't lost a pound. I also have a horrible taste in my mouth and frequent cramping in my left lower abdomen. I feel like there is something else I going on it's like my metabolism has come to a complete stop.