Is It Safe To Take Metrogyl And Zifi For Diarrhea During Pregnancy?

hi sir , my wife is pregnant and in secound trimister , so doctor advice , tab-metrogeyl 400 mg bd, and tab-zifi 200 mg bd,cap-vibact-ds bd, just want to ask , it is a correct treatment , for loose stool, what can i do , please guide me,regard-krushna