My Daughter Has Sever Crohns. She Has Tried All Of

My daughter has sever Crohns. She has tried all of the standard treatments as well as all of the biologics, which have worked but she eventually developed an
allergic reaction to them. She now has an ostomy and uncontrolled watery stools. She gets rehydration infusions a minimum of twice a week. Is there any option that will give her some sort of life? Her doctors keep going back to prednisone which helps some but doesnt hold when the dose is tapered down even slightly. This poor girl is 31 and suffering daily.