My Friend Has Leukoencephalopathy, Vanishing White Matter Disease. He Was

My friend has Leukoencephalopathy, Vanishing White Matter Disease. He was diagnosed first as ischemic disease and then in 2012 Leukoencephalopathy. In 2014, Alzheimer's Disease was added. He currently takes 10 mg of Namenda in the morning and 10 at night. He takes Diovan 160mg daily, Plavix, Meloxocam 12.5. He now has been put on Paroxetine He is on one tablet every third day as he often has extreme reactions to meds. It has decreased his anxiety and is less fearful of his condition getting worse. But it seems his memory is even impaired more. I worry that it is doing more damage. I would like your opinion.