My Hands And Around My Lips Burn, Itch And Crack.

My hands and around my lips burn, itch and crack. Once I apply a topical cream, currently "exederm" they will start to peal. Sometimes it wakes me up at night from the pain.
the skin literally cracks open. I have seen several dermatologist, but can't see to find the right combination of meds to heal the affected area.