My Husband Has Acute Lymphoblastic Leukemia And Relapsed Last Year

My husband has Acute Lymphoblastic leukemia and relapsed last year with isolated cns. The orignial diagnisis was only in the bone marrow. He has had a year of intrathecal chemo and does them once a month. He has had a headache for three days and now has a discharge coming out of the eyes. Could this be another relapse
Angel McGhee