My Husband Was Told By His Doctor That Hegg Oalongdarbyclor/

My husband was told by his doctor that hegg oalongdarbyclor/ has to change from metroprolol to edarbyclor 40 mg/25mg along with Nifdipine 90 mg, his been taking it for 3 months, but he gets cramps, and both legs swell up. am telling him to take half of each. can u recommend something? This would be the 3rd different type of blood medication he changed on him. My husband tells me he started with metreprolol 100 mg., because in 2008 he was dignoised with Colon Cancer and they found his heart was not functioning proboly.