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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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NTI SPERM ANTIBODY, SERUM @ (EIA) 26.83 U/mL <60.00 Comments

NTI SPERM ANTIBODY, SERUM
@
(EIA)
26.83
U/mL
<60.00
Comments
Sperm
antibody binding to head or tail antigens is considered specific for immunologic infertility.
These
antibodies
can be produced in both males and females affecting the fertility status. Spermatozoa are
separated
from the immune system in men by blood - testicular barrier. This barrier is breached in conditions
like
vasectomy, repeated infections, obstruction of the ducts, cryptorchidism, varicocele, trauma, torsion and
genetic
predisposition leading to development of anti sperm antibodies. In women non
-
specific
bacterial or viral
infections
produce antibodies which cross react with spermatozoan antigens. These antibodies affect sperm
motility,
penetration through cervical mucous, attachment of sperm to oocyte and actual sperm penetration and
fertilization
of oocyte. Possibility of autoimmune process in the development of sperm antibodies has also been
considered
posted on Wed, 18 Nov 2015
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