Patient Is Female 26 Months. Low Grade Fever 99 To

Patient is female 26 months. Low grade fever 99 to 100 nothing unmanageable. Restless during sleep hasn't eaten in 4 days drinks fluids and urinates no stools since she has stopped eating last one was on day 1 and was very loose. No vomiting, she will not drink supplement shakes, when should I be concerned