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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Seratonergic Toxicity. 6 Y/o 25 Kg Male Child With Autism

Seratonergic toxicity.
6 y/o 25 kg male child with autism taking Prozac and melatonin, exhibiting mild to moderate symptoms such as agitation, insomnia and behavioral difficulties. Cardiovascular signs normal, all symptoms appear to be CNS. 6 days out from receiving Fentanyl 25 mcg.
1. Could reducing Prozac dose by 50% improve this behavior without causing anti-depressant cessation syndrome or
2. implement cyproheptadine at 0.25mg/kg/day to inhibit 5-HT2a?

posted on Sat, 14 Apr 2018
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