Can thyroid problems, nodules, cause moles to change or appear? I had a very small tea stain irregular mole on my chest. I was very sweaty through the night I woke to find it was a blister on my chest. Pinkish puffy,the size of half a pea. The dermatologist was not alarmed and would see me again in a week. Should I insist on a biopsy? Could it be nodular?