Suggest Treatment For Hot Flashes And Leg Pain

Several years ago, I was mistakenly given too much premarin for hot flashes and evidentially my legs and knees started to hurt and ache. I have taken a bone density test and told that I have osteoporosis. I am sure that in taking too much premarin, it has caused a vitamin deficiency. Now I have white spots on my legs and my legs and knees hurt tremendously. What vitamin deficiency could this have caused? B12?