This Is More For Research. I'm Curious As To Find

This is more for research. I'm curious as to find out if the concentrate of medication, such as valium, can diminish from loss of blood. For example, two patients take a valium. After an hour the first patient is normal and the second patient has lost 4 liters of blood. Would a toxicology report show the same readings for both or would there be an inconsistency?