What Causes Delay In Periods,nausea,heart Burn And Sensitive Nipples?

I missed my period, and that NEVER happens, and now i've gotten to the point where i'm so tired i dont even want to get out of bed, i'm nauseas constantly, i've had heartburn for the first time ever, and my nipples are super duper sensitive. The pregnancy tests i've taken have all come out negative, but i took all of them within ten days of my missed period. could i be pregnant?