What Causes Delayed Periods?

Hi, I have a telephone app on Monday with a gp as my doctors is full for app at the moment but in 10 days late with my period which is very unusual as it s like clockwork once or twice been one or 2 days late but very rarely, I ve had no signs of my period coming and had 3 negative tests last one I did was Monday. I m starting I panick as to what could be wrong with me..