What Causes Headache And Tiredness While Having Pcod?

Hello. I have PCOS and have not had a regular period in about a year. About 3 months ago my husband and I stopped having protected sex because we would love to get pregnant. About 5 weeks ago I started geting headaches, feeling very sad, tired, nauseous, and just different. I was also getting cramps, but they were very different. I took a HPT and it was negative. About 3 weeks ago I started to get abnormal spotting and it has continued. I have taken two more HTP and they have been negative as well but I still have symptoms. I have a doctors appointment in 2 weeks, but should I wait. My body is telling me that there is something very different going on.