What Causes Recurring Insect Bite Like Blister?

HI, I HAD WHAT I THOUGHT WAS A SPIDER BITE ON MY SIDE UNDER MY UNDERARM. IT TOOK A FEW WEEKS TO HEAL AND I TOHUGHT I WAS DONE WITH IT, BUT NOW IT REOCCURRED SEVERAL MONTHS AFTER IT SEEMED TO HEAL. CAN A SINGLE SPIDER BITES HAVE REOCCURRING EFFECTS ON A PERSON? THANK YOUM