What Causes Severe Headaches Along With Swelling And Redness In Eye?

My wife is 48 years old she has very bad headaches bloodshot right eye and swollen eye 2 to 4 advil takes care of the pain for 2 to 4 hours but it always come back around the clock now she has been to family doctor eye doctor and had M R I this has been happening for over a year but in the last 2 months daily