What Could Ear Pain With Tiredness, Post A Flu Vaccine Suggest?

my 2-1/2 year old son developed a cold on Monday. Today (Friday) he got the flu mist vaccine. Within an hour he became very tired and complained his left ear hurt. He is not sleeping well tonight and the last time he was up said his other ear hurts. Not sure what to do as the weekend is here and dr's office is closed until Monday.....