Hi My Wife Has Been On Humira 40mg Adalimamab For

hi my wife has been on Humira 40mg Adalimamab for about 4 years. she suffers from Chrohns and has had 2 sections already. In the last 2 weeks she has started to be sick with liquids and solids coming back. This was how she was before the Humira I am wondering if it has stopped working. Her consultant is away on holidays and we are unable to get clarification from the junior doctors