Hi...just Got Released Yesterday From Hospital...long Story Short..have Picc And

hi...just got released yesterday from hospital...long story short..have picc and went to first infusion this a.m. and have been taking prescribed meds as well. was given belly shots for clots etc. till yesterday. left with compresion(?)socks on....had to take them off this afternoon.my feet/legs are swollen badly. have infusions scheduled every a.m. thru. the 14th and scheduled for follow-up tomorrow afternoon. should I be concerned enough to return to E.R. tonight?