My Husband Has Fibromyalgia, Lupus, Rheumatoid Arthritis, Pancreatitus, GERD, Colonitis,

my husband has fibromyalgia, lupus, rheumatoid arthritis, pancreatitus, GERD, colonitis, adrenal gland diffecency,ascending aortic anyerism,he has been experiencing alot of swelling lately...like for the last week & we cannot get it to got down no matter what we do...he has swelled in the past but nothing like this and it has always went down. He has had a shot of 50/50 (1/2 nubain/ 1/2 phenegren) & 2 toradol shots in the last week for pain. The swelling is getting even worse & is moving into his toes now......also his elbows are very swollen.....should I take him to the local ER