My Husband Is 66 Years Old And Underwent Bypass Surgery

my husband is 66 years old and underwent bypass surgery on august 25, 2015. six weeks later he had tavar surgery for his aortic valve. his mood swings and attitude have been so hard to deal with. he was a heavy smoker for 50 years and had to quit cold turkey. i want to know if these changes in him could also be caused by his meds. he is taking folic acid clopidogrel, atorvastatin, metropolol , aspirin, trasadone, alprasolam, and hydrocodon. can you tell me the side effects of these meds. thank you