Tom Brokaw’s Multiple Myeloma

Tom Brokaw of NBC news was a victim of Multiple Myeloma and has been receiving treatment. 1-4 in 100,000 people develop myeloma every year. It constitutes 1% of all cancers and is the second most common hematological malignancy in the U.S.

What is multiple myeloma ?

Multiple Myeloma, also known as plasma cell myeloma, is a cancer of plasma cells. Plasma cells produce antibodies and are a type of white blood cells. Multiple Myeloma usually arises in bone marrow and result in multiplication of plasma cells.

In Multiple Myeloma, abnormal plasma cells accumulate in bone marrow, thus interfering in the production of normal blood cells. In most cases, there happens to be production of paraprotein, which causes kidney problems.

What causes Multiple Myeloma ?

Scientists have no exact knowledge on the cause of this strange and deadly cancer. Researchers point out that it is more common in men, particularly with African-Americans.

What are the symptoms of Multiple Myeloma?

1. Weight loss
2. Excessive thirst, confusion due to hypercalcemia
3. Kidney problems
4. Bone pain
5. Weakness and fatigue

How is Multiple Myeloma Diagnosed?

Following tests are to be performed to ensure proper diagnosis :

1. Blood test
2. Bone marrow biopsy
3. Computerized Tomography (CT) scan
4. Urine electrophoresis
5. Serum protein

How is Multiple Myeloma Treated?

As of today, there is no known complete “cure” for multiple myeloma. However, recent advancements in medicine have successfully increased the life expectancy of patients diagnosed with multiple myeloma. The efficiency of the treatment depends on the stage at which the disease is detected. These are some of the common protocols:

1. Zoledronic acid is preferred for diagnosing patients with multiple myeloma.
2. Pamidronate or zoledronic acid should be used in patients with active disease.
3. For long-bone fractures, spinal cord compression and vertebral column instability Orthopedic Consultation is recommended.
4. Low-dose radiation therapy should be followed for palliation of uncontrolled pain.
5. Kyphoplasty must be considered for symptomatic vertebral compression fractures.