
Applying It To Entire Face. Becoming Very Red And Sore.

Probably contact dermatitis, a photo is needed to assess further.
Detailed Answer:
Hello dear,
welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.
Your symptoms seem to be related to a contact dermatitis.
It is probably caused by the exposure to fluorouracil cream.
It'll be better if you kindly upload a photo of the affected area so that I can review better.
For now, I suggest you to stop using the cream.
Wash your skin with a mild, fragrance-free soap and warm water.
Use a nonprescription cream containing 1 percent Hydrocortisone for relief.
Take antihistamines daily such as Benadryl.
Use cool compresses for several minutes.
If the symptoms continue you should visit a dermatologist for further evaluation.
Hope I have answered your query.
Let me know if I can assist you further

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