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Are Bisphosphonates Safe And Effective In Treatment Of Osteoporosis?
Question: If family doctor can refuse the referral patient to specialist? -I am after full replacement hip surgery and
I am concern about treatment of osteoporosis with Bisphosphonate Drugs ( is recommended Aclasta).
I understood about necessary treatment because density of my bone conform my medical problem.
But my past medical history included all possible side effects after treatment of SCLC my lung, made myself very aware to new experiment.Shortly;my cancer is in remission now (7 years ),since-
I was diagnosed with Hyperthyroid ,Graves's Disease,last 3 years Hypothyroidism, cataracts both eyes,,-
removed -performed 4 eyes surgery,recent osteoporosis.My general health has been compromised.
My vision problem until today has been not completely diagnose and thyroid unstable,hip surgery
was perform on emergency basis.All these information maybe explain the looking for second opinion in regarding new - for me medicine.
Thank you in advance
XXXXXXX
I am concern about treatment of osteoporosis with Bisphosphonate Drugs ( is recommended Aclasta).
I understood about necessary treatment because density of my bone conform my medical problem.
But my past medical history included all possible side effects after treatment of SCLC my lung, made myself very aware to new experiment.Shortly;my cancer is in remission now (7 years ),since-
I was diagnosed with Hyperthyroid ,Graves's Disease,last 3 years Hypothyroidism, cataracts both eyes,,-
removed -performed 4 eyes surgery,recent osteoporosis.My general health has been compromised.
My vision problem until today has been not completely diagnose and thyroid unstable,hip surgery
was perform on emergency basis.All these information maybe explain the looking for second opinion in regarding new - for me medicine.
Thank you in advance
XXXXXXX
Brief Answer:
bisphosphonates are first line therapy for the treatment of osteoporosis
Detailed Answer:
Hi
Bisphosphonates are drugs that inhibit mineralization or resorption of the bone by blocking the action of osteoclasts.
They are enzyme resistant analogues of pyrophosphate, which normally inhibits mineralization in the bone.
Their effect is dose dependent and they reduce the turnover of bone by inhibiting recruitment and promoting apoptosis of osteoclasts.
The bisphosphonates are first line therapy for the treatment of most patients with osteoporosis, with proven efficacy to reduce fracture risk at the spine, hip, and other nonvertebral skeletal sites.
Further bisphosphonates have been associated with a significant decrease in morbidity and increase in survival.
Regards
DR DE
bisphosphonates are first line therapy for the treatment of osteoporosis
Detailed Answer:
Hi
Bisphosphonates are drugs that inhibit mineralization or resorption of the bone by blocking the action of osteoclasts.
They are enzyme resistant analogues of pyrophosphate, which normally inhibits mineralization in the bone.
Their effect is dose dependent and they reduce the turnover of bone by inhibiting recruitment and promoting apoptosis of osteoclasts.
The bisphosphonates are first line therapy for the treatment of most patients with osteoporosis, with proven efficacy to reduce fracture risk at the spine, hip, and other nonvertebral skeletal sites.
Further bisphosphonates have been associated with a significant decrease in morbidity and increase in survival.
Regards
DR DE
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Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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