Are Diminutive Polyps Genetic Due To A Family History Of Colon Cancers?
 
                                    
                                    
                                          
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                                           Fri, 2 Mar 2018
                                           
                                        
                                        
                                        
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                                                Fri, 2 Mar 2018
                                                
                                            
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                                                Fri, 22 Dec 2023
                                                
                                                
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                                            Question : my Age is 35 / male
History
Taking pan d for the past 4 months
For reflux related issues
Last week had gastritis symptoms which was not responding to PPI
So doctor adviced for endoscopy
Finding
Diminutive polyp
H pylori negative
Family history
Grandfather died due to colon cancer age 75
My question
Can this polyp is related to genetic
Really scared after checking it on internet like FAP
Tissue sample sent for biopsy
But any idea what this can be
                            History
Taking pan d for the past 4 months
For reflux related issues
Last week had gastritis symptoms which was not responding to PPI
So doctor adviced for endoscopy
Finding
Diminutive polyp
H pylori negative
Family history
Grandfather died due to colon cancer age 75
My question
Can this polyp is related to genetic
Really scared after checking it on internet like FAP
Tissue sample sent for biopsy
But any idea what this can be
                                    Brief Answer:
As detailed below.
Detailed Answer:
Hi,
Grossly the diminutive polyp cannot be reliably distinguished from a hyperplastic pseudopolyp vs. a small true polyp (adenoma), and hence all such lesions are removed for microscopic analysis.
 
So the diminutive polyp in your case may be a hyperplastic small lesion.
If the lesion is single then this may not be related to genetics.
FAP have a typical appearance, hence should have been mentioned if present by your Endoscopist.
So stop worrying till the biopsy report is available.
Avoid the stress and anxiety as these can be one of the reasons for gastritis and reflux not responding to PPI.
Hope I have answered your query. Let me know if I can assist you further.
                                    
                            As detailed below.
Detailed Answer:
Hi,
Grossly the diminutive polyp cannot be reliably distinguished from a hyperplastic pseudopolyp vs. a small true polyp (adenoma), and hence all such lesions are removed for microscopic analysis.
So the diminutive polyp in your case may be a hyperplastic small lesion.
If the lesion is single then this may not be related to genetics.
FAP have a typical appearance, hence should have been mentioned if present by your Endoscopist.
So stop worrying till the biopsy report is available.
Avoid the stress and anxiety as these can be one of the reasons for gastritis and reflux not responding to PPI.
Hope I have answered your query. Let me know if I can assist you further.
 Above answer was peer-reviewed by :
                              
                            
                                  
                                      Dr. Vaishalee Punj
                                  
                              
                                         
 
                                    
                                    
                                
 
                                    Thankyou for your reply
I have sent pictures of my endoscopic result
Please send me ur comments
                            I have sent pictures of my endoscopic result
Please send me ur comments
                                    Brief Answer:
Please post reports of biopsy
Detailed Answer:
Hello,
Polyps look small without much signs of any dangerous problems.
Well, it is always the histopathology report that clears the doubts. Awaiting the reports.
Hope I have answered your query.
Take care
Regards,
Dr T Chandrakant, General Surgeon
                                    
                            Please post reports of biopsy
Detailed Answer:
Hello,
Polyps look small without much signs of any dangerous problems.
Well, it is always the histopathology report that clears the doubts. Awaiting the reports.
Hope I have answered your query.
Take care
Regards,
Dr T Chandrakant, General Surgeon
 Above answer was peer-reviewed by :
                              
                            
                                  
                                      Dr. Chakravarthy Mazumdar
                                  
                              
                                         
 
                                    
                                    
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