Are Elevated Vitamin-B12 And ALT Levels In My Annual Exam A Serious Concern?

Posted on Fri, 1 Jun 2018

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Fri, 1 Jun 2018 Answered on

Fri, 22 Jan 2021 Last reviewed on

Question : I recently had my annual exam done and have some odd results.
vitamin b12 was over 2000 ng/nl ref range was 200-1100. I do not take any b12 or multivitamins
Globulin was 1.8 g/dl ref range 1.9-3.7
Albumin/globulin ratio 2.7 range was 1.0-2.5
Ast 41 u/l ref range was 10-40
Alt 83 u/l ref range 9-46
Hemoglobin 17.4 g/dl ref range 13.2-17.1

Is this a serious sign something is wrong? I have noticed i dont fell that great these days. My doctor has put me in to get an uktrasound on my abdomen.

Answered by Dr. Monish De (1 hour later)

Brief Answer:
CT scan of upper abdomen

Detailed Answer:
Hi

Your vitamin B12 level is high.

Usually excess vitamin B12 is removed in the urine

Also your ALT is also high.

Increase in vitamin B12 level and ALT is caused by liver disease

I would advise you to do a CT scan of upper abdomen.

Also i would advise you to take Ursodeoxycholic acid tablet twice daily with your doctors advise.

If you have more queries i will be glad to help

Regards

Dr Monish De

Oncologist.

Above answer was peer-reviewed by : Dr. Yogesh D