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Are High Levels Of Anti-proteinase Antibodies, ESR And CRP Indicative Of Wegener's Granulomatosis?
Question: blood work i
sed 56hproteinase 3 2.6h
creactive protein 10.6h
results say wegeners
i am 60yr female
how do i know what stage
sed 56hproteinase 3 2.6h
creactive protein 10.6h
results say wegeners
i am 60yr female
how do i know what stage
Brief Answer:
Advice to undergo biopsy for confirmation of diagnosis
Detailed Answer:
Hello,
I have gone through your query and the attached report.
High Anti-proteinase 3 antibody, high ESR, Crp are suggestive of possible Wagner's granulomatosis.
Wagner's is an autoimmune vasculitic disorder which mainly affects ear, nose, lungs, skin, joints and kidney.
Confirmation of the diagnosis requires biopsy. Since Wagner's usually affects the nasal cavity, a biopsy from the nose is preferred as it is easily accessible.
The disease stage can vary from no symptoms to multiple organs affected.
From your blood report, the kidney function is normal, which means kidneys which is the target organ for Wagner's is not affected in your case.
However, detailed physical examination, chest Xray and pulmonary function testing are required to assess lung function and your general condition.
Management of Wagner's with corticosteroids and cyclophosphamide provide good results.
Please follow up with ent specialist as scheduled to discuss biopsy.
Hope I have answered your query.
Take care
Regards,
Dr Lekshmi Rita Venugopal, General & Family Physician
Advice to undergo biopsy for confirmation of diagnosis
Detailed Answer:
Hello,
I have gone through your query and the attached report.
High Anti-proteinase 3 antibody, high ESR, Crp are suggestive of possible Wagner's granulomatosis.
Wagner's is an autoimmune vasculitic disorder which mainly affects ear, nose, lungs, skin, joints and kidney.
Confirmation of the diagnosis requires biopsy. Since Wagner's usually affects the nasal cavity, a biopsy from the nose is preferred as it is easily accessible.
The disease stage can vary from no symptoms to multiple organs affected.
From your blood report, the kidney function is normal, which means kidneys which is the target organ for Wagner's is not affected in your case.
However, detailed physical examination, chest Xray and pulmonary function testing are required to assess lung function and your general condition.
Management of Wagner's with corticosteroids and cyclophosphamide provide good results.
Please follow up with ent specialist as scheduled to discuss biopsy.
Hope I have answered your query.
Take care
Regards,
Dr Lekshmi Rita Venugopal, General & Family Physician
Note: For further follow up on related General & Family Physician Click here.
Above answer was peer-reviewed by :
Dr. Raju A.T
Answered by
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