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Are Macrophages Ineffective In Patients Who Are Immunocompromised?

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Posted on Mon, 9 Feb 2015
Question: Thank you for your answer.
Now I understand your point.
one possible is only for if person has the problem for immunity.. so no inflammation happen and no encapsulation happen...
Last question is below.
What if the our macrophage could not engulf or eat the wood particle which being stuck in the layer of endocardium..and inflammation doesn't finished and continue... do you thnik what happen after 1yr and could we know easily at that time(eventhough that particle is very small? )this is my only optional thinking...if it is not possible... or inflammation doesn't finished and big problem happen.. I could finish my imagination....
Pls. explain me with medical knowledge..Thank you very much.
doctor
Answered by Dr. Dr. Ivan Romich (7 hours later)
Brief Answer:
hi again

Detailed Answer:
1. yes, this is possible in patients who are immunocomprmised as we see in AIDS, thrombocytopenia, hematologic diseases, immunodwficciencies etc. in their cases, immune system would not be reactive and inflammatory process wont take place.
this could lead to delayed complications related to foreign body in our body.

2. macrophages would be ineffective in patients that i ve mentioned above. in healthy people, inflammation should occur soon after detection of foreign body and this is from few hours to few days. such long delayed complication after 1 year isnt possible in healthy people. any foreign body cant be in our organisms without reaction of our white blood cells. this particle cant cause damage later in life, since it would be neutralised by immune system and enzymes. first,all bacterias that conaminated this particle would be killed,second wood would be dissolved.any mechanical damage to endocardium would happen right after incident. i hope i understood your question. feel free to ask.
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Ivan Romich

General Surgeon

Practicing since :2008

Answered : 13888 Questions

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Are Macrophages Ineffective In Patients Who Are Immunocompromised?

Brief Answer: hi again Detailed Answer: 1. yes, this is possible in patients who are immunocomprmised as we see in AIDS, thrombocytopenia, hematologic diseases, immunodwficciencies etc. in their cases, immune system would not be reactive and inflammatory process wont take place. this could lead to delayed complications related to foreign body in our body. 2. macrophages would be ineffective in patients that i ve mentioned above. in healthy people, inflammation should occur soon after detection of foreign body and this is from few hours to few days. such long delayed complication after 1 year isnt possible in healthy people. any foreign body cant be in our organisms without reaction of our white blood cells. this particle cant cause damage later in life, since it would be neutralised by immune system and enzymes. first,all bacterias that conaminated this particle would be killed,second wood would be dissolved.any mechanical damage to endocardium would happen right after incident. i hope i understood your question. feel free to ask.