Are Negative EIA Test And Chemiluminescence Test For STDs Post Oral Sex Conclusive?
Posted on
Wed, 3 Dec 2014
Medically reviewed by
Ask A Doctor - 24x7 Medical Review Team
Wed, 3 Dec 2014
Answered on
Mon, 29 Dec 2014
Last reviewed on
Question : I am a married man. This summer I stepped out of my relationship this summer - I received oral sex from a Chinese massage therapist around July 15th August 13th-I visit clinic. I was tested for Gonorrhea, Chlamydia, Syphilis, and HIV all results return negative (even though I was early for the syphilis window). I was also treated with Rocephin 250, 1g Azthromycin, and of course 2.4 MU BPG. On August 15,16th I had sex with my wife where we conceived. I was confident that i was fully covered from STD even though I had not cleared the window. I had read a post from Dr. Handsfield on medhelp saying that you are non infectious 24 hours after the shot of BPG (http://www.medhelp.org/posts/STDs/How-long-are-you-contagious-after-treatment-for-syphilis/show/0000) On 9/17 (4 weeks after last exposure) My wife has all her normal tests done with OB/GYN. To both of our suprise the RPR turns up positive (1:1) and the confirmatory done by chemiluminescence (which I though was weird) was negative. I freak out, tell her about the indsicretion She is tested for syphilis via RPR and EIA again 2 weeks later just over 6 weeks from our last sex(Which I have read on medhelp a number of times is conclusive via Dr. Handsfield). The doctor was satisfied but I had read the Trep-Sure test they used, would not be the best test during Primary syphilis.
Are these test sufficient for my wife?
Could I have passed syphilis to her even being treated about 48 hours before our sex
Are these test sufficient for my wife?
Could I have passed syphilis to her even being treated about 48 hours before our sex
Brief Answer:
Your wife is free of syphilis.
Detailed Answer:
Hi
Thank you for query. I am Dr Bharatesh D Basti answering your query.
As you are negative for syphilis in tests.
RPR biological false positive can occur due to various reasons even in pregnancy.
The EIA test and chemiluminescence tests are negative .They are both sensitive and specific.
So you can allay fears of syphilis.Your wife is free of syphilis.So there is no chance of you transmitting to your wife
You can allay all your anxiety. Forget about the episode.
You can get back for any clarification
Thank you
Dr Bharatesh D Basti
Dermatologist and venereologist
Your wife is free of syphilis.
Detailed Answer:
Hi
Thank you for query. I am Dr Bharatesh D Basti answering your query.
As you are negative for syphilis in tests.
RPR biological false positive can occur due to various reasons even in pregnancy.
The EIA test and chemiluminescence tests are negative .They are both sensitive and specific.
So you can allay fears of syphilis.Your wife is free of syphilis.So there is no chance of you transmitting to your wife
You can allay all your anxiety. Forget about the episode.
You can get back for any clarification
Thank you
Dr Bharatesh D Basti
Dermatologist and venereologist
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
I am most concerned that her follow up RPR was non reactive because of the general variance between titers. Is that absolute evidence that she is not infected.
Brief Answer:
Likely false positive. She is not infected.
Detailed Answer:
Hi
Thank you for follow up query.
It shows it is more likely false positive. As RPR titres do not come down so fast if infected and may increase also.
You can get back for any clarification
Thank you
Dr Bharatesh Basti
Likely false positive. She is not infected.
Detailed Answer:
Hi
Thank you for follow up query.
It shows it is more likely false positive. As RPR titres do not come down so fast if infected and may increase also.
You can get back for any clarification
Thank you
Dr Bharatesh Basti
Above answer was peer-reviewed by :
Dr. Prasad
Answered by
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