Are There Any Interactions Between Contrave And Lexapro?

Posted on Mon, 22 Aug 2016

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Mon, 22 Aug 2016 Answered on

Thu, 8 Sep 2016 Last reviewed on

Question : Hi, I recently started the prescription medicine Contrave. Can you please tell me if there are any contraindications for this drug with Lexapro or Xanax? Thank you.

Answered by Dr. Dr. Michelle Gibson (41 minutes later)

Brief Answer:
risk of interaction between the lexapro and contrave (bupropion aspect )

Detailed Answer:
HI, thanks for using healthcare magic

There is a risk of interaction between the contrave (a combination of bupropion and naltrexone ) and lexapro.

Lexapro is thought to increase the toxicity of the bupropion aspect of the contrave. There is a possible risk of reduced seizure threshold meaning that there is an increased risk of seizures.

Alternative would be best.

I hope this helps, feel free to ask any other questions

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar