Biopsy For Sarcoidosis Is Negative. Having Extreme Windedness When Bending Over, Blurred Vision And Acute Arthritis. Treatment?

Posted on Sat, 31 Aug 2013

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sat, 31 Aug 2013 Answered on

Thu, 26 Sep 2013 Last reviewed on

Question : I recently had a biopsy (lymph node taken from the left arm pit). Sarcoidosis was one of the posited diagnosis. The biopsy came back negative for Sarcoidosis; however, I continue to have the following worsening symptoms: intermittent but frequent windedness with any exertion; extreme windedness when bending over; rapidly worsening blurred vision; lethargy; weaknesses; acute arthritis manifested in the knees (at times swollen to the point that they looked physically deformed); intermittent swollen etremities that have been attributed to poorly functioning kidneys and bladder. Is it possible that the biopsy coud have yielded a false negative re scars??

Answered by Dr. Srikanth Reddy (2 hours later)

Hello
Thanks for using health care magic for posting your query.
I have through your query in detail and I can understand what you are going through.
No, it is very very unlikely that biopsy might have yielded a false negative result.
The other possible causes for your symptoms could be
1. Hypothyroidism: it explains most of your symptoms and it can be confirmed easily by doing a TSH test. If low the same can be corrected by thyroid supplementation.
2. Chronic renal failure. As you have stated that you have kidney issues your serum creatinine should be evaluated. It can also lead to anaemia and the symptoms that you you have stated.
3. Tuberculosis: It also explains most of your symptoms and you should investigated by a tuberculin skin test.
Hope that helps
Regards
Wish you good health.
Dr. Srikanth Reddy MD

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar