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Blood Test Done. Found Elevated Alkaline Phosphatase Level. Should I Be Concerned?

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Posted on Wed, 24 Apr 2013
Twitter Wed, 24 Apr 2013 Answered on
Twitter Fri, 17 May 2013 Last reviewed on
Question : Thank you. I just received some blood results from a health fair and my alkaline phosphatase tested at 137. Is this something I should be concerned about?
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Answered by Dr. Shoaib Khan (3 hours later)
Hello and welcome to XXXXXXX

Thank you for writing to us.

Alkaline phosphate (ALP) is a parameter used to check on the liver and/or the bone. When we have an increased ALP, the possible conditions could be:

1. Liver condition: When there are symptoms relating to a possible liver condition, then, along with the ALP we also look for any abnormalities in parameters like alanine aminotransferase(ALT), aspartate aminotransferase(AST) and bilirubin. An abnormality in these parameters, indicates a liver condition. This could be anything from an infection to a tumor. Thus further investigation will be required

2. Bone condition: If a bone condition is suspected then we will have to look in to parameters like calcium and phosphorus. If these parameters are abnormal, this points towards a bone condition resulting from increased bone activity. This could again range from a disease to tumors

Please also note that in rare cases when only the ALP is raised, the possible causes could be:
-Healing bone injuries (eg. fractures)
-Pregnancy
-Medication (eg. anti-epileptics, etc.)
and a few other conditions.

I would thus request you to first look into the other parameters mentioned above, and then consult your doctor for a follow up on the elevated ALP levels, in order to rule this harmless.

I hope you found my response helpful and informative. Do write back to me for any further clarifications, or you could rate my answers after closing this discussion.

Best wishes.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shoaib Khan

General & Family Physician

Practicing since :2009

Answered : 9409 Questions

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Blood Test Done. Found Elevated Alkaline Phosphatase Level. Should I Be Concerned?

Hello and welcome to XXXXXXX

Thank you for writing to us.

Alkaline phosphate (ALP) is a parameter used to check on the liver and/or the bone. When we have an increased ALP, the possible conditions could be:

1. Liver condition: When there are symptoms relating to a possible liver condition, then, along with the ALP we also look for any abnormalities in parameters like alanine aminotransferase(ALT), aspartate aminotransferase(AST) and bilirubin. An abnormality in these parameters, indicates a liver condition. This could be anything from an infection to a tumor. Thus further investigation will be required

2. Bone condition: If a bone condition is suspected then we will have to look in to parameters like calcium and phosphorus. If these parameters are abnormal, this points towards a bone condition resulting from increased bone activity. This could again range from a disease to tumors

Please also note that in rare cases when only the ALP is raised, the possible causes could be:
-Healing bone injuries (eg. fractures)
-Pregnancy
-Medication (eg. anti-epileptics, etc.)
and a few other conditions.

I would thus request you to first look into the other parameters mentioned above, and then consult your doctor for a follow up on the elevated ALP levels, in order to rule this harmless.

I hope you found my response helpful and informative. Do write back to me for any further clarifications, or you could rate my answers after closing this discussion.

Best wishes.