Can I Take Duromine And Fluvoxamine Together?

Posted on Sun, 21 Oct 2012

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sun, 21 Oct 2012 Answered on

Fri, 9 Nov 2012 Last reviewed on

Question : Can i take duromine and Fluvoxamine together? I am currently on fluvoxamine at 50mg dose per day. I am interested in taking duromine at either 15mg or 30mg per day but I am not sure if they interact with each other.

Answered by Dr. Saurabh Gupta (50 minutes later)

Hello,
Thanks for posting your query.

Fluvoxamine (Serotonin reuptake inhibitors) may interact with DUROMINE (Phentermine) by increasing serotonin levels. So DUROMINE should be used with caution if you are already taking Fluvoxamine.

Both of these medicines can increase the level of serotonin in your body. High serotonin levels may cause changes in body temperature, blood pressure and behaviour, leading to a medical condition called Serotonin Syndrome. Serotonin Syndrome may be life threatening.

Make sure your doctor know that you are taking these medicines together. If you experience muscle twitching, tremors, shivering or stiffness, fever, heavy sweating, heart palpitations, restlessness, confusion, agitation, trouble with coordination, or severe diarrhea contact your doctor right away. Your doctor may already be aware of this interaction and may be monitoring you for it.

Hope I have answered your query. Let me know if you have any more concerns.

Please accept my answer in case you do not have further queries.

Wishing you good health...
Regards

Above answer was peer-reviewed by : Dr. Prasad