Brief Answer: Keep a check on liver test Detailed Answer: Hello and welcome to HCM! I have read the question and can see that you are interested in knowing if you can take garcenia Cambogia while you are on Effexor, amitryptiline and bystolic. Firstly, I would like you to know that all herbal things are not suitable for everyone and also that it is not always what it looks like. There is always a balance of various combinations which help you - like you need all- water, food grains, vegetables, fruits in good proportions to remain healthy. For example- XXXXXXX is considered to be best fruit for health but can it alone give you good health? No. Garcenia Cambogia has side effects- on liver, so, you must check your liver function test before starting with it. And also repeat them after one or two weeks. This product has once been withdrawal from market because of the liver side effects (be on alert of you take it!). So, it will not be judicious for you to just go and invest too much in this product, you may try with very low amount and then gradually look at the response. It will be better that you continue with your medicines as such. So that you can relate the change with the new ingredient. It is a usually used for reducing the weight, but you have not mentioned why you want to take it. You are on anti hypertensive, so while you start with this new product, please monitor the blood pressure twice a day at least for initial few days. Hope the reply is useful for you please feel free to ask more queries for clarification If you feel satisfied, then kindly close the query and rate the answer Dr. Manisha Gopal MD Psychaitry Brief Answer: Explained below Detailed Answer: hello, I have read the earlier question but it was not very clear what you wanted to know, you did not ask anything related to the SSRi or TCAs specifically. It's ok, now I can understand what you want to ask. Look, there are two things, first if that I would never give a person of your age amitryptiline willingly. I would rather go for something like- sertraline, or escitalopram. They are more safe and have less interaction, plus cardio safe usually. Secondly, I do not understands why you are taking Venlafaxine ( Effexor) with amitryptiline ? only Venlafaxine should be enough for taking care of all the symptoms when given in appropriate dosage. Ideally, you should get the treatment revised by your doctor, discuss these points with him. He may agree to stop amitryptiline and increase Effexor - if required. This will be safer or he may shift to SSRI altogether. But there is no way that I can assure you that garcenia Cambogia is safe with any of them or for your liver. So, keep a check on liver tests while you take it. Hope the reply answers your query please feel free to ask more questions if you need more clarifications If you are satisfied, please close the questions and rate the answer Dr. Manisha Gopal MD psychiatry

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