Can Seroquel And Metformin Be Taken Together?

Posted on Mon, 30 Mar 2015

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Mon, 30 Mar 2015 Answered on

Mon, 20 Apr 2015 Last reviewed on

Question : I am on 100mg of seroquel for sleep following stressful divorce. I have mild PCOS my endo wants me on Metformin. A1C is 4.2. Can both meds be taken or no?

Answered by Dr. Binu Parameswaran Pillai (6 hours later)

Brief Answer:
METFORMIN IN PCOS

Detailed Answer:
Good day,
Noted your concern.

PCOS run a high risk of developing diabetes in the future. Metformiin is recommended in PCOS if the patient has glucose intolerence ( by an oral glucose tolerence test) or diabetes.

However, many endocrinologist ( including myself) prefer Metformin in PCOS which helps to regularise the periods by reducing the insulin levels. However, this is an offlabel treatment. Besides, Metformin induces Ovulation and improves chances of fertility. I have a blog on PCOS. You may please visit the blog " www.ovarypolycystic.blogspot.in

I can not comment further as i havent seen your full blood profile. However, your HbA1c seems to be very normal.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Binu Parameswaran Pillai (2 hours later)

If used off label to reduce insulin levels, what dose is appropriate?

Answered by Dr. Binu Parameswaran Pillai (11 minutes later)

Brief Answer:
Dose

Detailed Answer:
The maximum efficacy is seen with 1500 mg daily. However, not many patients can tolerate this dose. If you are obese, then this dose is okay. Otherwise, start on 500 mg once at night and over a period of time make 500 mg twice a day. Keep at that level for now

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar