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Can A Male With A+ And Female With O- Give Birth To O- Baby?

Posted on Wed, 3 Dec 2014

Question: 1. Can a male with A1+ and female with O- give birth to O- baby. What are the possible combinations (blood group & RH) a baby can have?
2. What are possible combination for baby (blood group and RH) for male with AB+ and female with O-
3. Can Question 1 and Question 2 have 2 different combination? If so please details

Answered by Dr. Robert Galamaga (31 minutes later)

Brief Answer:
Considerations.

Detailed Answer:
hello and thank you for sending the question.

It is certainly possible that the baby could be from this set of parents. Blood group type a may include both a and O characteristics. The Rh may only be present on one chromosome of the father so the father couldtransmit one of the Rh negative jeans to the baby along with the Rh negative XXXXXXX from the mother. In that case it is definitely possible.

if the father has blood type AB positive and mom is O- then baby could be A+, A-, B+ or B- since do not know if the father has both copies of the RH gene.

thanks again for sending your question.

Sincerely,

Dr. Galamaga

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Robert Galamaga (7 minutes later)

Hello Doctor,

Thanks for the reply.

Please let me know the possible baby blood group & RH type for Question 1.

Thanks.

Answered by Dr. Robert Galamaga (33 minutes later)

Brief Answer:
Considerations

Detailed Answer:
if the father is AO blood type as we assume then baby could be Apos A neg Opos or O negative.

if father is AA then baby is always type A - rh pos or rh neg if the mom is O negative.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Robert Galamaga (2 hours later)

Hello Doctor,

Sorry - I am bit confused...

Do you mean
if father is A1 positive and mom O negative = baby will be A negative or A positive? No other combination?

Please reply.

Answered by Dr. Robert Galamaga (41 minutes later)

Brief Answer:
Followup

Detailed Answer:
Depends on genotype of father. Father is either AA or AO. If father is AA then baby will always be type A - (AO genotype). If father is AO, however then baby can be either AO or OO (type O).

You need more details about genotypes of the parents because being Rh+ means you have at least one Rh gene - you could have two copies however. This influences the potential to pass the Rh gene along.

Do you have a specific reason for asking the question?

Thanks,

Dr. G

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Robert Galamaga (22 hours later)

Hello Doctor,

How can I test my Genotype? through normal blood test?

I am just trying to understand all possible combination for
1) father A1 positive mom O negative
2) father AB positive mom O negative

Answered by Dr. Robert Galamaga (14 hours later)

Brief Answer:
Followup

Detailed Answer:
You would have to request this from a special blood bank lab.

In question one: Baby will be either type A or type O

In question 2 - baby will be type A or type B

Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar