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Can Diffuse Idiopathic Skeletal Hyperostosis Increase Immature Granulocyte Counts In Blood?

Posted on Mon, 28 May 2018

Question: Hello I have recently been diagnosed with DISH, Diffuse idiopathic skeletal hyperostosis and also developed geographic tongue. My PCP ordered a CBC and vitamin level test to see if the tongue problem was attributed to anything obvious. When they called me they said everything looked normal when I looked at my results online I noticed that 2 things in the blood test were flagged as high. Thee absolute immature granulocyte count was .07 and the immature granulocyte relative percentage was 1.1. As I said they were flagged as high and I an confused as to why my doctor did not mention it as a problem. I did not fast before the blood draw. Thank you

Answered by Dr. Mirjeta Guni (53 minutes later)

Brief Answer:
Please attach the results;

Detailed Answer:
Hello and thank you for asking!
I have gone carefully through your concern.
Would you please attach the exams or the blood test that resulted abnormal?
Do you have symptoms of infection (fever, sweating, fatigue ect)?
Will be a pleasure to help you further.
Kind regards,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Yogesh D

Follow up: Dr. Mirjeta Guni (44 minutes later)

I have no fever, sweating or fatigue
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Cbc With Differential - Details
About This Test
Details
Past Results
Graph of Past Results
Component Results

Component
Your Value
Standard Range
Flag
Auto WBC
6.48 k/mcL
4.45 - 11.3 k/mcL

RBC
5.67 m/mcL
4.50 - 5.90 m/mcL

Hemoglobin
16.2 g/dL
14.0 - 17.4 g/dL

Hematocrit
48.5 %
41.5 - 50.4 %

MCV
85.5 fL
80.0 - 96.0 fL

MCH
28.6 pg
27.5 - 33.2 pg

MCHC
33.4 g/dL
33.4 - 35.5 g/dL

RDW
12.9 %
11.3 - 15.3 %

Platelets
249 k/mcL
145 - 445 k/mcL

MPV
9.4 fL
7.4 - 10.4 fL

Neutrophils Relative Percent
64.6 %
37.0 - 77.0 %

Lymphocytes Relative Percent
20.5 %
10.0 - 44.0 %

Monocytes Relative Percent
8.8 %
2.0 - 15.0 %

Eosinophils Relative Percent
4.2 %
0.0 - 7.0 %

Basophils Relative Percent
0.8 %
0.0 - 2.0 %

Immature Granulocytes Relative Percent
1.1 %
0.0 - 0.4 %
H
Absolute Neutrophil Count
4.19 k/mcL
2.0 - 9.3 k/mcL

Absolute Lymphocyte Count
1.33 k/mcL
0.6 - 3.4 k/mcL

Absolute Monocyte Count
0.57 k/mcL
0.0 - 1.5 k/mcL

Absolute Eosinophil Count
0.27 k/mcL
0.0 - 0.7 k/mcL

Absolute Basophil Count
0.05 k/mcL
0.0 - 0.2 k/mcL

Absolute Immature Granulocyte Count
0.07 k/mcL
0.0 - 0.03 k/mcL
H
Nucleated RBCs
0.0 /100 WBC
/100 WBC

Absolute Nucleated RBC Count
0.00 k/mcL
k/mcL

General Information
Collected:
12/27/2017 8:30 AM
Resulted:
12/27/2017 1:29 PM
Ordered By: XXXXXXX Barney, CRNP
Result Status:
Final result
This test result has been released by an automatic process.
Back to the Test Results List
XXXX® licensed from XXXX - 2016

I have no symptoms you described please advise

Hello I was hoping the blood test results went through, thank you

Answered by Dr. Mirjeta Guni (12 hours later)

Brief Answer:
About your blood results:

Detailed Answer:
Welcome back!
I've reviewed the reports,

A high relative count of different white blood cells subtypes is not taken into consideration if you do not have signs/ symptoms of infection, if you are not taking corticosteroids actually or do not suffer from any serious illness.

It is the absolute count that has a significant clinical importance since relative percentage can be misleading.

I would suggest checking a full blood count manually (not automatically) after 1 week to be 100 % sure that there is an alteration in the blood formula suggesting for infection.

Wishing you a Happy and Healthy New Year! Feel free to ask further.

Best wishes!
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Arnab Banerjee

Follow up: Dr. Mirjeta Guni (23 minutes later)

Hello thank you for your answer since I am not a doctor and will be relaying your message to my doctor what do you mean checking a full blood count manually verses automatically to be sure there is an alternation in the blood formula or will my doctor understand exactly what you are suggesting to do. Thank you so much and you have a Happy AND Healthy New Year also

Answered by Dr. Mirjeta Guni (17 minutes later)

Brief Answer:
it means checking a full blood count by a physician..

Detailed Answer:
Hello again!

It means the full blood count to be checked under the microscope by a physician and not to be checked by machines, as quite often they tend to give false results.

Best wishes,
Dr.Mirjeta

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Above answer was peer-reviewed by : Dr. Arnab Banerjee