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Can Intake Of Mirtazapine Along With Seroquel Causes Stuttering?

Posted on Fri, 12 Feb 2016

Question: My Son has been taking mirtazapine 30gms at night and Voxam Fluvoxzmine 100 mg. Recently as he went through a break up he has been taking valium and seroquel to sleep he noticed his speech hasn't been right and is stuttering. Could this mix effect his speech.is this an effect of a drug interaction

Answered by Dr. Seikhoo Bishnoi (22 minutes later)

Brief Answer:
This could be due to Seroquel

Detailed Answer:
Hello, Welcome to Health Care Magic

I can understand your concern. He is taking Mirtazapine and Fluvoxamine which are serotonergic drugs.

After his recent breakup he started taking Valium and Seroquel or Quetiapine which is an antipsychotic drug.

Though the drug is safe and doesn't cause extra pyramidal side effects but in some individuals who also take other psychoactive drugs it might result in slurred speech.

If possible ask him to reduce the dose of Quetiapine to 50 and his symptoms will improve or drugs like Trihexiphenidyl in low dose can help to reverse this side effect.

No need to worry. If possible talk to his doctor for reduction of doses.

Hope this helps you. If you have more doubts , feel free to ask again.

Thanks

Above answer was peer-reviewed by : Dr. Arnab Banerjee

Follow up: Dr. Seikhoo Bishnoi (28 minutes later)

I was really looking for confirmation that with his current 2 "prescribed drugs" Mirtazapine and Fluvoxamine, could taking the others be the cause of his slurred speech in particular the Seroquel?

He isn't on the valuim or Seroquel he only took it recently to help him sleep and took an extra dose last night to knock himself as he couldn't sleep and had to start work at 7 am. This morning was when his speech was worse. He doesn't take it on a regular bases.

I don’t know what Trihexiphenidy is or what serotonergic means. I am not a dr please answer with lay man terms
?

Answered by Dr. Seikhoo Bishnoi (4 hours later)

Brief Answer:
Reduce the dose of the drug

Detailed Answer:
Hi,

Serotonergic drugs are those drugs that are used in depression and anxiety and helps to increase serotonin in brain. These drugs are relatively safer drugs.

When Quetiapine was started with these drugs then this increased the risk of side effects of these drugs which resulted in slurred speech. Ask him to take the reduced doses of the Seroquel to prevent such side effects again.

Trihexiphenidyl is a medicine used to prevent side effects of antipsychotics like Quetiapine. As he is not regularly taking Seroquel so I don't think there is need for this drug.

Thanks, Hope this helps you, if you have more doubts you can ask again, don't hesitate.

Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Sonia Raina